FlorfenicolHe monofluoro hangai tēnei i ahu mai i te thiamphenicol, ko te tātai ngota ko C12H14Cl2FNO4S, he paura tioata mā, he mā rānei, kāore he kakara, he tino wairewa ki te wai me te chloroform, he iti te wairewa ki te waikawa acetic glacial, he wairewa ki te Methanol, te ethanol. He paturopi whānui hou tēnei o te chloramphenicol mō te whakamahinga kararehe, i angitu te whakawhanake i te mutunga o te tekau tau atu i 1980.
I te tau 1990 i hokohoko tuatahitia ai ki Hapani. I te tau 1993, i whakaaetia e Nōwei te rongoā hei rongoā i te furuncle o te hāmana. I te tau 1995, i whakaaetia e Parani, e te United Kingdom, e Austria, e Mexico me Spain te rongoā hei rongoā i ngā mate huakita manawa kau. Kua whakaaetia hoki kia whakamahia hei tāpiringa kai mā ngā poaka i Hapani me Mexico hei ārai me te rongoā i ngā mate huakita i roto i ngā poaka, ā, kua whakaaetia e Haina te rongoā inaianei.
He rongoā paturopi tēnei, e whakaputa ana i te pānga bacteriostatic whānui mā te aukati i te mahi a te peptidyltransferase, ā, he whānui hoki te whānuitanga o ngā rongoā paturopi, tae atu ki ngā momo rongoā rerekē.Gram-paime ngā huakita kino me te mycoplasma. Ko ngā huakita tairongo ko te Haemophilus kau me te poaka,Shigella dysenteriae, Salmonella, Escherichia coli, Pneumococcus, Influenza bacillus, Streptococcus, Staphylococcus aureus, Chlamydia, Leptospira, Rickettsia, me ētahi atu. Ka taea e tēnei hua te horapa ki roto i ngā pūtau huakita mā te wairewatanga lipid, ka mahi nui ki te wae 50s o te ribosome huakita 70s, ka aukati i te transpeptidase, ka aukati i te tipu o te peptidase, ka aukati i te hanganga o ngā mekameka peptide, ā, ka aukati i te hanganga pūmua, ka tutuki ai te kaupapa ārai huakita. Ka tere te mimiti o tēnei hua mā te waha, ka horapa whānuitia, he roa te haurua-ora, he nui te kukū o te rongoā i roto i te toto, ā, he roa te wā tiaki rongoā i roto i te toto.
I ngā tau tata nei, he maha ngā pāmu poaka iti me te rahi kua whakamahi i te florfenicol hei rongoā ahakoa te āhua o ngā poaka, ā, kua whakamahia te florfenicol hei rongoā makutu. Inaa, he tino morearea tēnei. He pai te pānga rongoā ki ngā mate poaka i puta mai i ngā huakita Gram-pai me te kino me te mycoplasma, inā koa i muri i te whakakotahitanga o te florfenicol me te doxycycline, ka kaha ake te pānga, ā, he whai hua ki te rongoā i te mekameka rhinitis poaka thoracic poaka. He pai te pānga rongoā o te Cocci, me ētahi atu.
Heoi, ko te take he mea morearea te whakamahi i te florfenicol i ngā wā katoa, he maha ngā pānga taha o te florfenicol, ā, ko te whakamahinga roa o te florfenicol he nui ake te kino i te pai. Hei tauira, kaua e warewarehia ēnei kōrero e ngā hoa poaka.
1. Mena kei te pāmu poaka ngā mate huaketo pēnei i te kirika poaka pseudorabies me te mowhiti taringa kikorangi, ka noho te whakamahinga o te florfenicol hei rongoā hei hoa mahi mō ēnei mate huaketo, nō reira, ki te pangia ēnei mate o runga ake nei, ā, ka pāngia anō hoki. Mēnā ka pangia e ētahi atu mate poaka, kaua e whakamahia te florfenicol hei rongoā, ka kino ake te mate.
2. Ka whakararuraru a Florfenicol i tā tātou pūnaha toto, ā, ka aukati i te hanga o ngā toto whero i roto i te hinu wheua, inā koa mēnā he makariri, he pupuhi rānei ngā hononga o ā tātou poaka ngote. Kāore te tae o te huruhuru poaka i te ātaahua, he huruhuru parai, engari he tohu anō hoki o te anemia, ka kore hoki te poaka e kai roa, ka pakari ai.
3. He paitini te Florfenicol ki ngā kukune. Mēnā ka whakamahia pinepinetia te florfenicol i te wā e hapu ana ngā poaka kau, ka mate ngā pi.
4. Ka pāngia ngā poaka e ngā mate puku me te mate korere mēnā ka roa te whakamahinga o te florfenicol.
5. He ngāwari te pā mai o te mate tuarua, pērā i te mate kiriuhi i puta mai i te mate staphylococcus i roto i ngā poaka, te mate tuarua rānei o ētahi mate kiriuhi harore.
Hei whakarāpopototanga, kaua te florfenicol e whakamahia hei rongoā noa. Mēnā ka whakamahia ētahi atu paturopi kāore e pai te pānga, ā, he rerekē te whakamahinga (te pei i te huaketo), ka taea te whakamahi i te florfenicol me te doxycycline hei taha. Ka whakamahia te acupuncture hei rongoā i ngā mate uaua, ā, kāore i te tūtohutia mō ētahi atu āhuatanga.
Wā tuku: Hurae-14-2022