FlorfenicolHe paturopi whānui te Florfenicol, he pai te pānga ārai ki ngā huakita Gram-pai me ngā huakita kino. Nō reira, he maha ngā pāmu poaka e whakamahi ana i te florfenicol hei ārai, hei rongoā rānei i ngā poaka mēnā he maha ngā mate e pāngia ana. Ka whakamahia e ngā kaimahi kararehe o ētahi pāmu poaka te horopeta nui o te florfenicol hei rongoā, hei ārai rānei i ngā mate ahakoa te mate, ahakoa te rōpū, te wāhanga rānei. Ehara te Florfenicol i te rongoā whakaora, ā, me whakamahi tika kia tutuki ai te hua e hiahiatia ana. Kei raro nei ka whakamāramahia e mātou te whakamahinga o te florfenicol, me te tumanako ka āwhina i te nuinga o ngā kaimahi poaka:
1. Ngā āhuatanga ārai huakita oflorfenicol
1. He whānui rawa te whānuitanga o ōna patu huakita, ā, he kaha tōna pānga whakamate i ngā huakita Gram-pai me ngā huakita kino, tae atu ki ngā huakita Gram-pai anaerobic me ngā spirochetes kino, rickettsia, amoeba, me ētahi atu. He kaha tōna pānga patu huakita.
2. E whakaatu ana ngā whakamātautau in vitro me in vivo he pai ake te kaha o tōna mahi patu huakita i ngā rongoā patu huakita o nāianei.
3. He tere te mahi a te florfenicol, ā, ka taea e ia te eke ki te kukū rongoā whakaora i roto i te toto i te 1 hāora i muri i te werohanga ā-ringa, ā, ka taea te eke ki te kukū rongoā tino teitei i roto i te 1.5-3 hāora; ka taea te pupuri i te kukū rongoā toto whai hua, roa te mahi mō te neke atu i te 20 hāora i muri i te kotahi horopeta.
4. Ka taea e ia te uru atu ki te arai toto-roro, ā, ko tōna pānga rongoā ki te meningitis huakita kararehe kāore e taea te whakataurite ki ētahi atu rongoā paturopi.
5. Kāore he paitini, kāore hoki he pānga taha ina whakamahia i te nui kua tūtohutia, ka wikitoria i te tūponotanga o te anemia aplastic me ētahi atu paitini i puta mai i te thiamphenicol, ā, kāore e kino ki ngā kararehe me ngā kai. Ka whakamahia mō te mate o ngā wāhanga rerekē o te tinana i puta mai i te huakita i roto i ngā kararehe. Te maimoatanga, tae atu ki te aukati me te rongoā i ngā mate manawa huakita, te meningitis, te pleurisy, te mastitis, ngā mate puku me te mate postpartum i roto i ngā poaka.
2. Ngā huakita ngoikore oflorfenicol
1. Ngā mate poaka e pai ake ai te florfenicol
E taunakitia ana tēnei hua hei rongoā pai mō te niumōnia poaka, te mate pukupuku kiri poaka me te mate Haemophilus parasuis, inā koa mō te rongoā i ngā huakita e ātete ana ki ngā fluoroquinolones me ētahi atu paturopi.
2. Ka taea hoki te whakamahi i te Florfenicol hei rongoā i ngā mate poaka e whai ake nei
Ka taea hoki te whakamahi hei rongoā i ngā mate manawa e puta mai ana i ngā momo Streptococcus (pneumonia), Bordetella bronchiseptica (atrophic rhinitis), Mycoplasma pneumoniae (swine asthma), me ētahi atu; salmonellosis (glet paratyphoid), colibacillosis (glet asthma), ngā mate o te ara nakunaku pērā i te enteritis i puta mai i te korere kōwhai, te korere mā, te mate edema poaka) me ētahi atu huakita tairongo. Ka taea te whakamahi i te Florfenicol hei rongoā i ēnei mate poaka, engari ehara i te rongoā pai mō ēnei mate poaka, nō reira me tino tupato te whakamahi.
3. Te whakamahinga hē oflorfenicol
1. He nui rawa, he iti rawa rānei te horopeta. He paitini ngā horopeta nui, ā, kāore e whai hua ngā horopeta iti.'
2. he roa rawa te wā. Ko ētahi whakamahinga roa o ngā rongoā me te kore here.
3. te whakamahinga o ngā taonga, ngā hapa wāhanga. Ka whakamahia noatia e ngā poaka hapū me ngā poaka whakamomona aua rongoā, ka puta he paitini, he toenga rongoā rānei, ka hua ake he hanga me te kai haumaru kore.
4. Te hototahitanga koretake. He maha ngā wā ka whakamahia e ētahi tāngata te florfenicol me ngā sulfonamides me ngā cephalosporins. Me tūhura mēnā he pūtaiao, he whaitake hoki.
5. Kāore te whāngai ranu i whakaohokia kia ōrite, ā, kāore he pānga o te rongoā, o te paihana rānei o te rongoā.
Tuawhā, te whakamahinga oflorfenicolngā mahi whakatūpato
1. Kaua tēnei hua e whakamahia ngātahi me ngā macrolides, ngā lincosamides me ngā paturopi diterpenoid semi-synthetic – Tiamulin, ka puta he pānga taupatupatu ina whakamahia ngātahitia.'
2. Kāore e taea te whakamahi tahi i tēnei hua meβ-ngā lactone amines me ngā fluoroquinolones, nā te mea he huakita tere te mahi a tēnei hua e aukati ana i te hanganga pūmua huakita, ā, ko te mea whakamutunga he patu huakita tere te mahi i te wā whakaputa uri. I raro i te mahi a te mea tuatahi, ka tere te aukati i te hanganga pūmua huakita, ka mutu te tipu me te whakanui o ngā huakita, ā, ka ngoikore te pānga patu huakita o te mea whakamutunga. Nō reira, ina hiahiatia he pānga whakamate tere te maimoatanga, kāore e taea te whakamahi ngātahi.
3. Kāore e taea te whakaranu i tēnei hua ki te sulfadiazine sodium mō te werohanga ā-roto. Kaua e whakamahia tahitia me ngā rongoā kawakore ina tukuna ā-waha, ā-roto rānei, kia kore ai e pirau, kia kore ai hoki e pakaru. Kāore hoki e pai mō te werohanga ā-roto me te tetracycline hydrochloride, kanamycin, adenosine triphosphate, coenzyme A, me ētahi atu, kia kore ai e maroke, kia kore ai hoki e heke te whai huatanga.
4. Tērā pea ka pā te ngoikore me te pirau o ngā uaua i muri i te werohanga ki roto i te uaua. Nō reira, ka taea te werohanga tauutuutu ki ngā uaua hōhonu o te kaki me te papa, ā, kāore i te tūtohutia kia werohangahia anō i te wāhi kotahi.
5. I te mea he paitini pea tēnei hua ki ngā kukune, me tūpato te whakamahinga mō ngā kau uha e hapu ana, me ngā kau uha e whāngai ana.
6. Ina teitei te pāmahana tinana o ngā poaka mate, ka taea te whakamahi me ngā rongoā whakaheke wera me te dexamethasone, ā, ka pai ake te pānga.'
7. I roto i te ārai me te rongoā i te mate manawa poaka (PRDC), ka tūtohu ētahi i te whakakotahitanga o te florfenicol me te amoxicillin, te florfenicol me te tylosin, me te florfenicol me te tylosin, he mea kāore e tika ana, nā te mea mai i te tirohanga rongoā, kāore e taea te whakamahi ngātahi i ngā mea e rua. Heoi, ka taea te whakamahi ngātahi i te florfenicol me ngā tetracycline pēnei i te doxycycline.'
8. He paitini toto tēnei hua. Ahakoa kāore e puta he anemia aplastic kore e taea te whakaora i te hinu wheua, he nui ake te pānga o te aukati erythropoiesis whakahurihuri i te chloramphenicol (hauā). Kāore e whakaaetia kia hoatu i te wā werohanga, i ngā kararehe rānei he mate ārai mate kino.'
9. Mā te whakamahinga roa ka pāngia pea koe e ngā mate nakunaku me te korenga o ngā huaora, te mate pāwera nui rānei.'
10. Me tūpato te ārai me te rongoā i ngā mate poaka, me te hoatu i te rongoā kia rite ki te horopeta kua whakaritea me te huarahi maimoatanga, ā, kaua e whakamahia kinotia hei karo i ngā pānga kino.'
11. Mō ngā kararehe he ngoikore ō rātou whatukuhu, me whakaiti te horopeta, me whakaroa rānei te wā hoatutanga.'
12. Mēnā he iti te pāmahana, ka kitea he puhoi te tere whakarewa; he maturuturunga iho rānei o te florfenicol i roto i te otinga kua whakaritea, he iti noa te whakamahana (kaua e neke atu i te 45℃), ka taea te whakarewa tere i ngā mea katoa. Ko te otinga kua oti te whakarite he pai ake te whakamahi i roto i ngā haora 48.'
He tino haumaru te whakamahi i te momo horopeta e tika ana e ai ki te whakataki i runga ake nei, me te tirotiro i te horopeta kua tūtohutia. Tērā pea ka pāngia ia kararehe e te ngaronga hiahia mō te wā poto, te iti o te inu wai, te korere rānei, te mamae iti i te wāhi i werohia ai ki roto i te uaua me ngā tauhohenga kiko iti, he mea noa katoa ēnei, ā, ka hoki anō ki te āhua noa i muri i te whakamutu i te rongoā.
Wā tuku: Maehe-28-2022