He whenua pārūrū a Initonīhia, ā, he wāhi whakatipuranga pai mō ngā waeroa. Nā te tere nui o te whakaputa uri o ngā waeroa kua akiakihia ngā mahi hei whakatika i tēnei raruraru, ko tētahi o ēnei ko te whakamahi i ngā rongoā ārai waeroa—ngā patu pepeke me ngā momo matū.
Kei roto i ngā koiri waeroa ngā matū hohe maha, pērā i te d-allethrin, trans-flufenicol, bioallethrin, dimethoate, pyrifluquinazone, d-phenetrin,te hipermetīrini,he isoprenepyrine rānei, he matū pyrethroid katoa ēnei. He patu pepeke rauropi ngā matū pyrethroid ka taea te aukati i ngā pepeke mā te paitini i ō rātou pūnaha io. Kei te wātea ngā koiri namu hei mea hokohoko hei rehu, hei koiri, hei whakapūhui, hei ārai hiko hoki.
Ka taea e te nui rawa o te whakamahinga o ngā koiri waeroa me ētahi atu patu pepeke te mea he kore mōhiotanga tika. Ka pā pea ēnei hua kino ki te tangata, ki te taiao, me ngā waeroa anō hoki. I whakaatuhia e ngā rangahau o mua a Almahdi et al. (2014) me Rahayuningsih (2006) ko te pānga o ngā koiri waeroa kei roto te trans-fluorometholone ki ngā kiore hapu ka hua ake he āhua kino o te pēpi me te taumaha iti i te whānautanga. E whakaatu ana tēnei he pānga kino pea ngā koiri waeroa ki ngā wāhine hapu, nā te mea he nui ake te aro o ngā wāhine ki ngā matū i te wā e hapu ana.
Ka taea te whakamahi i ngā kiore hei kararehe taiwhanga i roto i ngā rangahau teratogenicity e aro ana ki te kohi mōhiohio mō ngā āhua kino o te kukune i puta mai i te pānga ki ngā rongoā ārai namu i te wā o te organogenesis. Kei te hiahia ngā kairangahau ki te ako atu i ngā pānga teratogenic o ētahi atu rongoā ārai namu kei roto te permethrin hei matū hohe ki te taumaha, te roa o te tinana, me ngā rerekētanga āhua o ngā kukune kiore (Mus musculus). Mā te manawa roa o ngā patu pepeke ka arahi ki te paitini me te whakaputa i ngā rerekētanga toto, matū koiora, me te cytokine, tae atu ki te kino o ngā kiko mutagenic.
Ko te whāinga o tēnei rangahau he whakatau i ngā pānga whakamate o te ārai hiko ki ngā kukune kiore (Mus musculus). Ko te ārai hiko i whakamahia he 0.566% (4.2 mg/mL) o te matū hohe permethrin, i hongihia e ngā kiore hapu i te wā o te organogenesis (ngā rā 6-15 o te haputanga). E toru tekau ngā kiore hapu i wehea matapōkeretia kia rima ngā rōpū (e ono ngā tārua i ia rōpū): rōpū C (rōpū mana, kāore i te pāngia e te ārai hiko); rōpū T1 (4 hāora o te pāngia e te ārai hiko i ia rā); rōpū T2 (6 hāora o te pāngia e te ārai hiko i ia rā); rōpū T3 (8 hāora o te pāngia e te ārai hiko i ia rā); me te rōpū T4 (10 hāora o te pāngia e te ārai hiko i ia rā). I inehia te taumaha o te kukune me te roa o te tinana, ā, i mahia te tātaritanga tatauranga mā te whakamahi i te tātaritanga rerekētanga kotahi-ara (ANOVA) me te whakamātautau whakatairite maha a Duncan. I whakamahia ngā whakamātautau Kruskal-Wallis me Mann-Whitney hei tātari i ngā reiti whānautanga ora (%), ngā whānautanga mate (%), me ngā āhua rerekētanga o te tinana (%). Kāore i kitea he rerekētanga āhua o te tinana i ngā hua, engari i kitea he toto kiri papatahi. I kitea he rerekētanga nui i roto i te taumaha me te roa o te kukune, ngā reiti whānautanga ora (%), ngā whānautanga mate (%), me te toto (%) (p<0.05). Ko ngā reiti teitei rawa o te mate me te toto i roto i te kōpū i kitea i muri i te 10 hāora o te pānga ki ngā koiri waeroa hiko i ia rā.
Wā tuku: Pipiri-04-2026
